Mayflower Medicinals currently operates three dispensary locations across Massachusetts: a dual-license (medical and recreational) facility in Boston's Allston neighborhood, and recreational-only locations in Worcester and Lowell. All three dispensaries are supplied by their fully-operational cultivation and processing facility in Holliston, giving them complete vertical integration from seed to sale.The brand offers a comprehensive product lineup including flower, pre-rolls, edibles, vaporizers, concentrates, tinctures, topicals, CBD products, and accessories. Their menu features both in-house cultivated strains known for consistent quality and unique genetics, alongside a carefully curated selection of other Massachusetts-local brands. This "boutique dispensary" approach creates an intimate shopping environment where knowledgeable staff can help customers find exactly what they need.Mayflower's Holliston facility utilizes sophisticated automated systems for lighting, fertigation, and environmental controls, enabling high production levels while maintaining premium quality standards. The facility was designed to be one of the most advanced in the United States when it opened, featuring commercial kitchen capabilities for edible production alongside their nine grow rooms dedicated to cultivating distinctive strains.
Mayflower Medicinals planted its roots in Massachusetts in 2016 when it received two provisional licenses to operate medical dispensaries in the Commonwealth. Founded with backing from iAnthus Capital Holdings, the brand quickly established itself as a patient-first operation dedicated to bringing premium medical cannabis to New England communities.Construction began on their state-of-the-art 36,000-square-foot cultivation and processing facility in Holliston in early 2017, with first harvest following later that year. In July 2018, Mayflower opened its flagship medical dispensary in Boston's Allston neighborhood, becoming just the second license holder to operate within the city limits—a significant milestone in a competitive market.The brand continued its strategic expansion with a Worcester recreational location in December 2020, followed by a Lowell dispensary in 2021. Throughout this growth, Mayflower has remained committed to being locally rooted, with most team members hailing from Massachusetts and leadership deeply involved in daily operations. This homegrown approach has allowed them to understand and serve their communities authentically while maintaining their founding mission of nurturing patients through Earth's favorite flower.
Mayflower Medicinals operates with a clear mission: to nurture others by producing the finest cannabis products from Earth's favorite flower. As a patient-first organization, they're committed to providing the highest-quality medical cannabis products and services in a safe, secure, and professionally managed environment.Beyond product excellence, Mayflower demonstrates a deep commitment to social equity and justice through their comprehensive Positive Impact Plan. This multi-faceted initiative includes a paid Fellowship Program providing industry training to individuals from communities disproportionately impacted by cannabis prohibition, the Mayflower Artist Spotlight Series (M.A.S.S.) supporting local artists, Community Gardens focused on urban beautification, and Skills Seminars offering education on cultivation and business principles.Mayflower also actively supports the Last Prisoner Project through their Roll It Up For Justice program, allowing customers to contribute to cannabis justice reform efforts. Their values prioritize not just cannabis quality, but meaningful community impact and social change.
What sets Mayflower Medicinals apart is their authentic commitment to being a Massachusetts brand, for Massachusetts people. Unlike many multi-state operators, Mayflower's team is locally rooted, bringing genuine understanding of New England cannabis culture and patient needs to every interaction.Their vertical integration means deal-seekers get exceptional value—products move directly from their Holliston facility to dispensary shelves without middleman markup. The combination of consistent in-house cultivation and thoughtfully selected partner brands creates diverse menus with something for every budget and preference.But it's their Positive Impact Plan that really resonates with us. Mayflower doesn't just talk about social equity—they actively create opportunities through paid fellowships, artist partnerships, and community programs. When you shop at Mayflower, you're supporting a brand that genuinely invests in repairing the harms of prohibition while delivering quality cannabis at competitive prices. That's a combination worth celebrating.